PrEP (pre-exposure prophylaxis) has changed the landscape of HIV prevention dramatically for gay and bisexual men in India and worldwide. When taken correctly, it reduces HIV transmission risk by over 99%. But PrEP isn't the complete picture of sexual health — and lube plays a role that even PrEP users often overlook.
What PrEP does and doesn't do
PrEP (typically tenofovir disoproxil fumarate/emtricitabine, sold as Truvada or its generics) works by maintaining antiretroviral drug levels in bloodstream and mucosal tissue high enough to prevent HIV from establishing infection even if exposure occurs.
What PrEP doesn't protect against:
- Gonorrhoea
- Chlamydia
- Syphilis
- Herpes (HSV-1 and HSV-2)
- HPV
- Hepatitis A and B (vaccines exist for both)
For gay men in India on PrEP, STI rates — particularly gonorrhoea and syphilis — have increased as condom use has declined. This is a global pattern. STI testing every 3 months is the standard recommendation for anyone on PrEP.
How lube reduces STI risk beyond PrEP
STIs like gonorrhoea, chlamydia, herpes, and syphilis transmit through two mechanisms: direct contact with infected secretions, and through microscopic breaks in mucosal tissue caused by friction.
This is where lube comes in. Using a good water-based lube in India during anal sex reduces the friction that causes rectal microtears — the same tears that facilitate STI transmission. Lube doesn't prevent STIs the way condoms or PrEP do, but it meaningfully reduces tissue damage that creates transmission opportunities.
The combination of PrEP + condoms + personal lubricant + regular testing is the most comprehensive sexual health approach currently available.
PrEP access in India
PrEP became more accessible in India after generic versions were approved. It's available through:
- The Humsafar Trust and affiliated clinics (Mumbai)
- Government ART centres (free but with varying availability)
- Private prescriptions from HIV-treating physicians
- Some NGOs working in LGBTQ health
The standard dose is one tablet daily, taken every day regardless of sexual activity. Condom use is strongly recommended alongside PrEP for comprehensive STI protection.
The mental health dimension
HIV anxiety remains significant in gay communities in India, even among those on PrEP. This anxiety can affect sexual health decisions, relationship dynamics, and willingness to seek care. Organisations like iCall and Vandrevala Foundation offer LGBTQ-affirming mental health support.
slyp is committed to being a gay lube brand in India that engages seriously with community health — not just as a product, but as part of a broader conversation about queer wellbeing.
Shop slyp — India's body-safe, condom-compatible personal lubricant.